I assume that you mean militarily, since he did "resist" by corrupting Numenor.
An in-depth answer to this question is not feasible, since all we know about the relative strengths of Numenor and Mordor is that the former's might was overwhelming to the point where Sauron's forces declined to fight and fled, even though he had the Ring!
So, militarily, the answer appears to be no.
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Beleriand, Beleriand,
the borders of the Elven-land.
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