Although it's hardly an indication of a widely used trade-route, it's interesting to note that Bilbo gave away plenty of toys out of Dale for his birthday party. The Dwarves (supposedly) who delivered them might have been party-guests too but I find it a little hard to believe that they would make such a journey for pleasure only.
Actually I think that trade between Dwarves and Hobbits of the Shire must have been rather commonplace, although most Shire-folk had little of no direct contact with Dwarves. I don't see the Dwarves of the Blue Mountain being much for farming but they would still be in need of agricultural produce. If they don't grow crops themselves that only leaves the Elves of Lindon and the Hobbits of the Shire as realistic trade partners. With an eye for profit, wouldn't the Dwarves get a better deal in the Shire than in the Gray Havens, seeing that their exclusive goods (like clocks) must have been be more fancy and luxurious for the lowly Hobbits than for the lofty Elves.
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"You can always come back, but you can't come back all the way" ~ Bob Dylan
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