Well, I think pairs would be exciting, but there might be two problems: if one person disappears it can be quite fatal. And also if there are pairs I think the time to answer the questions should be longer. Those problems, though, can be overcome. I don't know if I'd prefer pairs or groups of four. Both have their pors and cons. Hmmm... You others can decide.
And if we're having teams of four, what are they? Those I proposed?